Research Associate Support Resource – Molecular Biology & Cell-based Assay-SUB-AKH-003
South San Francisco
Contract (mandatory): 12 months + (possible extension) Small Description: The contractor Research Associate will support the Analytical Development team within the Tech Dev department by developing, optimizing, and executing molecular biology and cell-based assays. The role involves hands-on laboratory work, data analysis, documentation, and cross-functional collaboration in a hypothesis-driven R&D environment at the South San Francisco facility. Job Responsibilities: Develop, optimize, and execute analytical assays for proteins, DNA, adeno-associated viral (AAV) nanoparticles, and related cell-based assays. • Perform routine testing using established SOPs and applicable regulatory guidelines, including ddPCR/qPCR, ELISA, and mammalian cell-based assays. • Support assay transfer to internal partners (QC, testing, and research teams), including documentation, troubleshooting, and method comparability. • Analyze experimental data, assess data quality, determine applicability to project goals, draw conclusions, and make data-driven recommendations. • Author, review, and revise experimental procedures, protocols, and technical reports. • Maintain accurate, timely, and compliant records of analytical development activities in laboratory notebooks, ELN, and data systems. • Summarize and present experimental results in meetings and participate in report writing. • Contribute to a collaborative laboratory environment by sharing technical insights, supporting cross-functional projects, and improving workflows. Skills: Proficiency in mammalian cell-based assays and PCR-based assays (qPCR, ddPCR). • Hands-on experience performing quantitative assays such as ELISA for characterization of proteins, nucleic acids, viruses, or other biological products. • Strong experience with sterile technique and mammalian cell culture, including cell maintenance, expansion, characterization, and banking. • Working knowledge of molecular biology techniques including DNA/RNA/protein isolation, cDNA synthesis, RT-PCR, qPCR, and digital PCR. • Ability to independently plan, execute, troubleshoot, and document experiments in a fast-paced, collaborative environment. • Strong analytical thinking, attention to detail, and commitment to generating high-quality, reproducible data. • Excellent written and verbal communication skills for presenting technical data to technical and non-technical audiences. • Proficiency with Microsoft Office and standard data analysis and documentation tools. Preferred Skills: • Experience working with Adeno-Associated Virus (AAV). • Experience in analytical method development and assay transfer. • Experience in basic statistical analysis. Qualification: B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline. • 1+ years of industry experience in pharmaceutical or biotechnology environments. Apply